Ampullary Cancer a Very Rare Form of Cancer 壺腹癌罕見 每十萬人約0.3-0.46人患病

Lee Ying-yuan lost his battle to ampullary cancer on Nov. 11. Doctors say this type of cancer doesn't present with symptoms in the early stages, therefore is highly deadly.


Ampullary cancer took the life of Lee Ying-yuan on Nov. 11. This rare type of cancer affects 0.3 to 0.46 out of every 100,000 people. By the time symptoms like jaundice and noticeable weight loss occur, the cancer has likely already obstructed the bile and pancreatic ducts. This type of cancer is very difficult to operate on. 

Hsu Wen-lu, Chief of General Surgery, Taiwan Adventist Hospital: “Because of their small size, tumors often escape notice on sonograms and scans. Unless you have symptoms and seek medical attention for them, (this form of cancer is not easily discovered). By the time you have symptoms, it may be inoperable).”

The ampulla of Vater is the place in the small intestine where the pancreatic and bile ducts and duodenum intersect. According to research, 70 percent of ampullary cancer cases start with a benign tumor that turns cancerous. If the cancer has already spread to the lymph nodes, the five-year survival rate is just 25 to 40 percent.

Lai Gi-ming, Executive Director, Formosa Cancer Foundation: “Many patients are only diagnosed because of frequent stomach pain and unexplained weight loss. By that time, the cancer has usually already metastasized to, first, the lymph nodes and second, the liver. The prognosis is not good at this point.”

Doctors say the risk factors for this form of cancer are unknown, making it difficult to prevent. However, people that experience unexplained stomach pain and those with a family history of glandular cysts should get annual endoscopies along with exercising and eating a healthy diet.

 

 

 

 

前駐泰國代表李應元11日晚間因為「壺腹癌」病逝,享壽68歲。醫師表示「壺腹癌」是罕見癌症,每十萬人僅有0.3到0.46人患病,早期幾乎沒有症狀,但等到出現黃疸、體重明顯下降時,往往腫瘤已經塞住膽管和胰管,且腫瘤位置不容易手術。

台安醫院一般外科主任許䰚勎表示:「因為它的腫瘤太小了,所以一般來講我們在掃腹部超音波,或是掃一些電腦斷層的時候,基本上不太能夠發現它。」許䰚勎補充,「除非你有症狀,因為你有症狀才會就醫嘛,所以這個時候可能它已經當你有症狀的時候,可能已經不能開(手術)了。」

醫師說所謂「壺腹」是位於膽管、胰管與十二指腸交會處,就像是三叉路口,當此處的括約肌長出腫瘤就稱為「壺腹癌」,目前醫界研究發現有七成致病原因是由良性腺瘤惡化而來,若晚期淋巴轉移,患者5年存活率只有25%到40%。

台灣癌症基金會執行長賴基銘表示:「肚子痛、開始消瘦,然後才發現,哇,旁邊都擴散出去了。」賴基銘又說,「淋巴擴散是第一步,第二步就是跑到肝臟,這是我們最常見的,如果一旦是這樣,那他的預後就很差。」

醫師強調,針對「壺腹癌」危險因子的研究並不多,也較難預防,只能從臨床症狀加以判斷,如果持續不明原因、劇烈腹痛,有腺性息肉症家族病史者,建議每年定期照胃鏡檢查,平時也要養成多運動、均衡飲食的良好習慣。

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