A study conducted by Kaohsiung Chang Gung Memorial Hospital has found that combining the spike proteins of the SARS coronavirus and the COVID-19 coronavirus may result in more effective vaccines.
People wait to see thoracic doctors. Kaohsiung Chang Gung Memorial Hospital previously conducted a study to analyze the antibody responses in employees who were vaccinated. It unexpectedly discovered that people who recovered from SARS and received one dose of the AZ vaccine had an antibody concentration that was 8.5 times that of people who received two AZ doses and never had SARS.
Chen I-chun, Dep. Director, Infectious Diseases Dept., Kaohsiung CGMH: “The antibody value for employees who received one Moderna dose (and recovered from SARS) was 10,000 to 20,000. For those who received one AZ dose, the value was several thousand to 10,000.”
The hospital conducted tests on 11 employees that were infected with SARS in 2003. It found that immune memory persisted in people who recovered from SARS. COVID-19 vaccines aren't effective for long and boosters are needed. Doctors say combining the spike proteins of the SARS coronavirus and the COVID-19 coronavirus may result in more effective vaccines for longer periods.
Li Yun-chi, Director, Infectious Diseases Dept., Kaohsiung CGMH: “A similar study was also done in Singapore. Generally speaking, the serum neutralizing antibodies of people who recovered from SARS and who received the Pfizer-BNT vaccine were pretty effective against this coronavirus and even other coronaviruses that infect mammals.”
The results of the study have already been published in an American medical journal. Doctors caution that Hong Kong's current epidemic situation is severe because the elderly vaccination coverage rate is low and there are numerous variants. Therefore, people should get fully vaccinated even if they previously recovered from SARS.